Just to get the ball rolling on this: here's the layouts I use for our home poker league. The first is before the tournament starts and the second is during the game.
http://www.oregonpokertour.com/OPTLayoutPreT.jpghttp://www.oregonpokertour.com/OPTLayout.jpgThese aren't amazingly creative or anything . . . but hey . . . they work for us.

The Pre-Tournament design really is all about getting the important information to everyone without having the switch screens every five seconds. I like doing this more than having the screens rotate beetween the tournament window and the seating chart, even though TD2.0 can do that. This is nicer I think.